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| Status |
Public on Jun 12, 2014 |
| Title |
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We profiled basal and bicuculline+4-AP inducible mRNA expression in cultured mouse hippocampal neurons with or without viral shRNA mediated knockdown of Kdm6b
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| |
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| Overall design |
We harvested mRNA from neurons under four conditions (pLKO vector/treatment control, pLKO vector/3hr bicuculline+4AP, Kdm6b knockdown/treatment control,Kdm6b knockdown/3hr bicuculline+4AP). Libraries were generated and used for RNA sequencing.
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| |
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| Contributor(s) |
Wijayatunge R, Chen L, Cha YM, Zanna AS, Frank CL, West AE |
| Citation(s) |
24983519 |
| |
| Submission date |
Jun 11, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Christopher L Frank |
| E-mail(s) |
chris.frank21@gmail.com
|
| Organization name |
Duke University
|
| Lab |
Gregory Crawford
|
| Street address |
101 Science Dr.
|
| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27708 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA252502 |
| SRA |
SRP043113 |
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