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Series GSE58356 Query DataSets for GSE58356
Status Public on Jun 11, 2014
Title Axiom® Exome 319 Array data to identify susceptible genetic variations of gastric cancer
Organism Homo sapiens
Experiment type SNP genotyping by SNP array
Genome variation profiling by SNP array
Summary To efficiently identify genetic susceptibility variants for gastric cancer, including rare coding variants, we performed an exome chip-based array study. We found that a linkage disequilibrium (LD) block containing 2 significant variants in PSCA gene increased the risk and two blocks that included 15 suggested variants including TRIM31, TRIM 40, TRIM 10, and TRIM26 regions, and included one suggested variant and OR2H2 gene showed protective associations with gastric cancer susceptibility. In addition, the PLEC region (rs200893203), FBLN2 region (rs201192415), and EPHA2 region (rs3754334) were associated with increased susceptibility
Overall design We performed an exome chip-based array study in 329 gastric cancer cases and 683 controls.
Contributor(s) Kim J, Park B, Lee J, Cho YA, Woo HD, Jeong SH, Lee JE, Shin ES, Choi IJ, Kim YW
Citation(s) 30189721
Submission date Jun 10, 2014
Last update date Apr 16, 2022
Contact name Boyoung Park
Organization name National Cancer Centerm Korea
Street address 323 Ilsan-ro, Ilsandong-gu, Goyang-si
City Gyeonggi-do
ZIP/Postal code 410-769
Country South Korea
Platforms (1)
GPL18760 [Axiom_Exome319] Affymetrix Human Axiom Exome 319 Genotyping Array
Samples (1012)
GSM1408142 Blood_1_1022
GSM1408143 Blood_0_577
GSM1408144 Blood_0_578
BioProject PRJNA252114

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE58356_RAW.tar 12.7 Gb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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