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| Status |
Public on Aug 03, 2014 |
| Title |
Required Enhancer: Matrin-3 Structure Interactions for Homeodomain Transcription Programs |
| Organism |
Rattus norvegicus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Other
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| Summary |
Study of the POU-homeodomain transcription factor, has revealed that, binding of Pit1-occupied enhancers to a nuclear matrin-3-rich network/architecture is a key event in effective activation of the Pit1-regulated enhancer / coding gene transcriptional program.
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| Overall design |
All ChIP-seq(s) were designed to understand the unique features, associated molecular mechanisms and functions of Matrin3 in the Homeodomain transcription study. Gro-seq Samples are used to detect gene expression between knockdown control and knockdown two key factors in our study.
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| |
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| Contributor(s) |
Skowronska-Krawczyk D, Ma Q |
| Citation(s) |
25119036 |
| |
| Submission date |
May 27, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Qi Ma |
| E-mail(s) |
q1ma@ucsd.edu
|
| Organization name |
UCSD
|
| Street address |
9500 Gilman Dr,
|
| City |
San Diego |
| ZIP/Postal code |
92093 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL10287 |
Illumina Genome Analyzer II (Rattus norvegicus) |
| GPL14844 |
Illumina HiSeq 2000 (Rattus norvegicus) |
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| Samples (11)
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| Relations |
| BioProject |
PRJNA248882 |
| SRA |
SRP042370 |
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