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Series GSE57816 Query DataSets for GSE57816
Status Public on May 27, 2014
Title Exposure of rat to a variety of toxicants, thigh muscle assayed by Affymetrix microarray
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary DrugMatrix is a comprehensive rat toxicogenomics database and analysis tool developed to facilitate the integration of toxicogenomics into hazard assessment. Using the whole genome and a diverse set of compounds allows a comprehensive view of most pharmacological and toxicological questions and is applicable to other situations such as disease and development.
Overall design Complete Drug Matrix dataset for rat thigh muscle. Approximately 600 different compounds were profiled in up to 7 different rat tissues by obtaining tissue samples from test compound-treated and vehicle control-treated rats in biological triplicates for gene expression analysis after 0.25, 1, 3, and 5 days of exposure with daily dosing. In a few studies (1.8%), 7 days of exposure was substituted for 5 days of exposure. Samples were hybridized to whole genome RG230_2.0 rat GeneChip arrays (Affymetrix, CA).
Contributor(s) Auerbach S
Citation(s) 25058030
Submission date May 20, 2014
Last update date Jul 31, 2017
Contact name Scott Auerbach
Organization name National Institute of Environmental Sciences
Street address 111 T.W. Alexander Drive
City Research Triangle Park
State/province NC
ZIP/Postal code 27709
Country USA
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (158)
GSM1394406 S020506-017_ORAL GAVAGE_CMC_3 d_Male_101042.CEL
GSM1394407 S020415-209_ORAL GAVAGE_CMC_3 d_Male_101055.CEL
GSM1394408 S020617-383_SULPIRIDE_1000 mg/kg_ORAL GAVAGE_CMC_5 d_Male_101059.CEL
This SubSeries is part of SuperSeries:
GSE57822 Drug Matrix Data - Affymetrix Arrays
BioProject PRJNA248177

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE57816_RAW.tar 405.8 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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