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| Status |
Public on Apr 10, 2014 |
| Title |
Comparison of haploid and diploid clones of KBM7 cancer cell line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The series were performed to study the changes in gene expression upon diploidization of KBM7 cancer (CML) cell line. The line can exist either as a clone with 24 chromosomes (nearly haploid) or with
48 chromosomes (nearly diploid). Gene expression patterns are largely ploidy-independent, as suggested by this experiment
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| Overall design |
Single cell derived clones of KBM7 cell line were grown. Included 7 haploid and 10 diploid clones, each with 2 independent total RNA extraction/microarray run. Also included peripheral blood mononuclear cells (PBMC) samples for comparison purposes.
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| Contributor(s) |
Smurnyy Y, Feng Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 02, 2014 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Yegor Smurnyy |
| Organization name |
Novartis Institutes for Biomedical Research
|
| Street address |
250 Massachusetts Ave
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02139 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (38)
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| Relations |
| BioProject |
PRJNA243373 |
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