|
| Status |
Public on Apr 27, 2016 |
| Title |
Orphan Nuclear Receptor ERRγ is required for pancreatic islet beta-cell maturation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We characterized the effect of loss of ERRγ expression in mouse pancreatic islets using adenoviral constructs.
|
| |
|
| Overall design |
Total RNA was extracted from Ad-EGFP or Ad-Cre infected pancreatic islets from ERRγfl/fl mice. Gene expression profiles were compared between the wild-type control (Ad-EGFP) and ERRγKO (Ad-Cre) islets.
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| |
|
| Contributor(s) |
Yu RT, Yoshihara E, Evans RM |
| Citation(s) |
27076077 |
| Submission date |
Mar 20, 2014 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Ruth T Yu |
| Organization name |
Salk Institute
|
| Department |
Gene Expression Lab
|
| Lab |
Ronald Evans
|
| Street address |
10010 N Torrey Pines Rd
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
| Samples (4)
|
| GSM1354760 |
ERRγfl/fl mouse pancreatic islets infected with adenovirus EGFP, technical replicate 1 |
| GSM1354761 |
ERRγfl/fl mouse pancreatic islets infected with adenovirus EGFP, technical replicate 2 |
| GSM1354762 |
ERRγfl/fl mouse pancreatic islets infected with adenovirus Cre, technical replicate 1 |
| GSM1354763 |
ERRγfl/fl mouse pancreatic islets infected with adenovirus Cre, technical replicate 2 |
|
| Relations |
| BioProject |
PRJNA242357 |
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