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| Status |
Public on Mar 14, 2014 |
| Title |
Severe Hypoxia Exerts Parallel and Cell-specific Regulation of Gene Expression and Alternative Splicing in Human Mesenchymal Stem CellsMesenchymal Stem Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To identify the effects of hypoxia on stem cell populations, we subjected human mesenchymal stem cells to a pO2 of 4 mmHg and analyzed global gene expression and alternative splicing (AS) by genome-exon microarray.
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| Overall design |
Hypoxia induced gene expression in human mesenchymal stem cells was measured at 24 hours after exposure to 0.5% oxygen or normal 21% oxygen. Three independent experiments were performed per condition (Hypoxia or Normoxia).
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| Contributor(s) |
Shehadeh L, Webster K |
| Citation(s) |
24758227 |
| |
| Submission date |
Mar 13, 2014 |
| Last update date |
Jun 13, 2014 |
| Contact name |
Lina A Shehadeh |
| E-mail(s) |
lshehadeh@med.miami.edu
|
| Organization name |
University of Miami
|
| Department |
Medicine
|
| Street address |
1501 NW 10 Ave
|
| City |
Miami |
| State/province |
FL |
| ZIP/Postal code |
33136 |
| Country |
USA |
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| Platforms (1) |
| GPL14552 |
Agilent-028679 SurePrint G3 Human Exon 4x180K Microarray (Probe Name Version) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA241189 |
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