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Series GSE55756 Query DataSets for GSE55756
Status Public on Mar 17, 2014
Title Transcription profiling of mouse liver by array
Organism Mus musculus
Experiment type Expression profiling by array
Summary PPARα-null and wild-type male mice treated with PFHxS or PFNA
 
Overall design PPARα-null and wild-type male mice at 6-9 months of age were dosed by gavage for 7 consecutive days with either 0, 3, or 10 mg/kg  PFHxS, or 1 or 3 mg/kg PFNA (#394459, Sigma-Aldrich, St, Louis, MO) in water.  PFHxS was kindly provided by 3M Corp (St. Paul, MN).  Four biological replicates consisting of individual animals were included in each dose group.  Dose levels reflected exposures that produce hepatomegaly in adult mice without inducing overt toxicity.
 
Contributor(s) Rosen M
Citation(s) 26215100
Submission date Mar 10, 2014
Last update date Feb 11, 2019
Contact name Mitch Rosen
Organization name U.S. EPA
Street address MD 72
City Research Triangle Park
State/province NC
ZIP/Postal code 27711
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (47)
GSM1342840 Liver_PPARα Knockout_PFHxS Vehicle_Rep1
GSM1342841 Liver_PPARα Knockout_PFHxS Vehicle_Rep2
GSM1342842 Liver_PPARα Knockout_PFHxS Vehicle_Rep3
Relations
BioProject PRJNA240894

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE55756_RAW.tar 139.6 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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