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Series GSE55618 Query DataSets for GSE55618
Status Public on Dec 16, 2014
Title Toxicogenomic profiling in the whole zebrafish embryo after exposure to reference hepatotoxicants.
Organism Danio rerio
Experiment type Expression profiling by array
Summary Zebrafish embryos have been proposed as an attractive alternative model system for hepatotoxicity testing.
In this study we determined gene expression responses after exposure to reference hepatotoxicants and controls to identify biomarkers for hepatotoxicity.
 
Overall design 188 samples; hepatotoxic compounds at 3 concentrations and with multiple replicates; negative controls at single concentration and with multiple replicates; water (DSW) and 0.2% DMSO vehicle control.
 
Contributor(s) Pennings J, Driessen M
Citation(s) 25448281
Submission date Mar 05, 2014
Last update date Dec 16, 2014
Contact name Jeroen Pennings
E-mail(s) Jeroen.Pennings@rivm.nl
Phone +31 88 689 2214
Organization name Natl. Inst. Public Health & Environment
Street address A. van Leeuwenhoeklaan 9
City Bilthoven
ZIP/Postal code 3721MA
Country Netherlands
 
Platforms (1)
GPL18378 [ZebGene-1_1-st] Affymetrix Genechip Zebrafish ST Genome Array 1.1, brainarray version 15 [zebgene11st_Dr_ENTREZG]
Samples (188)
GSM1340265 Isoniazid, 5 mM. sample 001
GSM1340266 Isoniazid, 1.67 mM. sample 002
GSM1340267 DMSO, 0.2 %. sample 003
Relations
BioProject PRJNA240229

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE55618_RAW.tar 918.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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