|
| Status |
Public on Mar 10, 2014 |
| Title |
Probing In vivo Brachyury Function with Tc mouse model |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To identify Brachyury target genes in vivo and elucidate how Brachyury-mediated regulation contributes to early mouse developmental homeostasis and coordination, we performed mRNA-seq to compare gene expression profiles of WT and Tc/Tc embryos at both E7.5 ~ 8.0 and E10.0 ~ 10.5
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| |
|
| Overall design |
WT and Tc/Tc embryos were isolated at both E7.5 ~ 8.0 and E10.0 ~ 10.5. Subsequently, directional mRNA-seq expriments were performed with wild-type and Tc/Tc whole embryos
|
| |
|
| Contributor(s) |
Zhe L |
| Citation(s) |
24616493 |
| |
| Submission date |
Feb 13, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Zhe Liu |
| E-mail(s) |
liuz11@janelia.hhmi.org
|
| Organization name |
Howard Hughes Medical Institute
|
| Department |
Janelia Farm Research Campus
|
| Lab |
Liu
|
| Street address |
19700 Helix Dr.
|
| City |
Ashburn |
| State/province |
Virginia |
| ZIP/Postal code |
20147 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (4)
|
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| This SubSeries is part of SuperSeries: |
| GSE54985 |
Charting Brachyury-mediated Developmental Pathways During Early Mouse Embryogenesis |
|
| Relations |
| BioProject |
PRJNA238199 |
| SRA |
SRP037764 |
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