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Series GSE54597 Query DataSets for GSE54597
Status Public on Feb 01, 2014
Title Dose-response modeling of early molecular and cellular key events in CAR-mediated hepatocarcinogenesis pathway
Organism Mus musculus
Experiment type Expression profiling by array
Summary Male and female CD-1 mice were administered dietary Phenobarbital for 2 or 7 days. In-life, enzyme activity, cell proliferation, genomic analysis, and Bench-mark dose modeling was carried out.
The goal was to exmaine low-dose PB effects on early key events in CAR-mediated hepatocarcinogenesis.
 
Overall design PB at 0, 0.15, 1.5, 15, 75, or 150 mg/kg-day for 2 or 7 days to characterize multiple apical and molecular endpoints.
 
Contributor(s) Geter DR, Bhat V, Gollapudi BB, Sura R, Hester SD
Citation(s) 24449422
Submission date Jan 31, 2014
Last update date Feb 11, 2019
Contact name Susan Hester
E-mail hester.susan@epa.gov
Phone 919-541-1320
Organization name US EPA
Street address 109 TW Alexander Dr
City RTP
State/province NC
ZIP/Postal code 27711
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (96)
GSM1319714 Female_0.15ppmPB_Day2_Rep1
GSM1319715 Female_0.15ppmPB_Day2_Rep2
GSM1319716 Female_0.15ppmPB_Day2_Rep3
Relations
BioProject PRJNA237112

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE54597_RAW.tar 334.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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