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GEO help: Mouse over screen elements for information. |
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Status |
Public on Jan 23, 2014 |
Title |
Cistrome profiles of Retinoids x Receptor alpha (RXRα) , Retinoic Acid Receptor alpha (RARα), and Retinoic Acid Receptor beta (RARβ) in livers of mice treated by control and retionic acid-containing diet |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
Comparison between ChIP-Seq data of RARα and RARβ, between RAR and RXR, as well as between control and retinoic acid-treatment for each investigated nuclear receptors.
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Overall design |
Mouse were treated by control diet and RA-diet for 1 days. After treatment, livers were used to do ChIP using antibodies of RXRα, RARα, and RARβ. An aliquote of total chromatin without pull-down process by any antibodies was used as input control. A single-end read of 35bp sequencing was performed on each of ChIPed DNA and input. Sequencing data of RARα and RARβ were compared to each other. In addtional, each of RARα and RARβ data were compared with RXRα data. For each nuclear receptor, ChIP-Seq data prior or after RA-treatment were also compared with each other.
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Contributor(s) |
Wan Y, He Y, Zhan Q, Lu Y, Liu H |
Citation(s) |
23981290, 24833708 |
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Submission date |
Dec 31, 2013 |
Last update date |
Aug 16, 2019 |
Contact name |
Yuqi He |
E-mail(s) |
hyqjeff@gmail.com
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Organization name |
UC Davis Medical Center
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Street address |
Rm3400, Research III, UC Davis Medical Center, 4645 2nd Ave
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City |
Sacramento |
State/province |
California |
ZIP/Postal code |
95817 |
Country |
USA |
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Platforms (1) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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Samples (7)
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GSM1299601 |
RARa binding in the RA-treatment group |
GSM1299602 |
RARb binding in the RA-treatment group |
GSM1299603 |
RXRa binding in the RA-treatment group |
GSM1299604 |
Input for control and RA-treatment groups |
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Relations |
BioProject |
PRJNA232748 |
SRA |
SRP034854 |
Supplementary file |
Size |
Download |
File type/resource |
GSE53736_RAW.tar |
3.4 Mb |
(http)(custom) |
TAR (of BED) |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
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