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Series GSE51576 Query DataSets for GSE51576
Status Public on Oct 02, 2014
Title Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior
Organism Acromyrmex echinatior
Experiment type Other
Expression profiling by high throughput sequencing
Summary Eusocial insects have evolved the capacity to generate adults with distinct morphological, reproductive and behavioural phenotypes from the same genome. Recent studies suggest that RNA editing might enhance the diversity of gene products at the post-transcriptional level, particularly to induce functional changes in the nervous system. Using head samples from the leaf-cutting ant Acromyrmex echinatior, we compare RNA editomes across eusocial castes, identifying ca. 11,000 RNA editing sites in gynes, large workers and small workers. Those editing sites map to 800 genes functionally enriched for neurotransmission, circadian rhythm, temperature response, RNA splicing and carboxylic acid biosynthesis. Most A. echinatior editing sites are species specific, but 8–23% are conserved across ant subfamilies and likely to have been important for the evolution of eusociality in ants. The level of editing varies for the same site between castes, suggesting that RNA editing might be a general mechanism that shapes caste behaviour in ants.
Overall design Analysis of genome-wide RNA editing in three different female castes of the the leaf-cutting ant Acromyrmex echinatior.
Contributor(s) Li Q, Wang Z, Lian J, Schiøtt M, Jin L, Zhang P, Zhang Y, Nygaard S, Peng Z, Zhou Y, Deng Y, Zhang W, Boomsma JJ, Zhang G
Citation(s) 25266559, 27538485
Submission date Oct 23, 2013
Last update date Jul 18, 2019
Contact name Hong zhi Cao
Phone 8675525274032
Organization name BGI-SHENZHEN
Department Bioinformatics
Street address F5, Main Building, Beishan Industrial Zone, Beishan Road, Yantian District
City Shenzhen
State/province Guangdong
ZIP/Postal code 518083
Country China
Platforms (1)
GPL17823 Illumina HiSeq 2000 (Acromyrmex echinatior)
Samples (18)
GSM1248666 RNA_Ae322_gyne_heads
GSM1248667 DNA_Ae322_gynes_bodies
GSM1248668 RNA_Ae356_gyne_heads
BioProject PRJNA223531
SRA SRP031846

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Supplementary file Size Download File type/resource
GSE51576_9samples.RNAediting.site_07292014.txt.gz 655.1 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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