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Series GSE51547 Query DataSets for GSE51547
Status Public on May 17, 2015
Title DNA methylation in melanoma is connected to gene expression phenotypes and MITF pathway expression.
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary We subjected 50 stage III/IV tumors and 9 melanoma cell lines to genome-wide methylation analysis using the Illumina Infinium Human Methylation450 BeadChip. Furthermore, we used two technical replicates of light, medium, dark melanocyte, dermal epidermis and fibroblasts (Science Cell Research, USA), and one sample of peripheral blood leukocytes (Promega).
 
Overall design Bisulphite converted DNA from the 50 stage III/IV tumors, 9 melanoma cell lines as well as normal cells were hybridised to the Illumina Infinium Human Methylation450 Beadchip.
 
Contributor(s) Lauss M, Harbst K, Jönsson G
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Oct 22, 2013
Last update date Mar 22, 2019
Contact name Martin Lauss
Organization name Lund University
Department Dept of Oncology
Street address Barngatan 2B
City Lund
ZIP/Postal code 22185
Country Sweden
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (70)
GSM1247733 genomic DNA from Sample MM44
GSM1247734 genomic DNA from Sample MM37
GSM1247735 genomic DNA from Sample MM04
Relations
BioProject PRJNA223404

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE51547_RAW.tar 183.1 Mb (http)(custom) TAR
GSE51547_unmethylated_methylated_raw.txt.gz 166.2 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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