|
| Status |
Public on Oct 19, 2013 |
| Title |
ERG induced mesenchymal like gene signature |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
ERG overexpression was conducted in stably transfected K562 cell line with a tet-on inducible plasmid habouring ERG3. Prolonged induction of ERG (8 days) produced spindle cell shape changes whereas non-induced cells retained the round morphology. In oder to determine the genes responsible for inducing cell shape changes, a genome wide transcriptional screen was conducted.
|
| |
|
| Overall design |
Three clones that potently induced ERG overexpression (8 days) with the corresponding non-induced cells were hybridized.
|
| |
|
| Contributor(s) |
Mochmann LH, Neumann M, Nowak V, Hofmann WK, Baldus CD |
| Citation(s) |
24504051 |
| |
| Submission date |
Sep 27, 2013 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Claudia D Baldus |
| E-mail(s) |
claudia.baldus@charite.de
|
| Organization name |
Charite
|
| Department |
Hematology and Oncology
|
| Lab |
Claudia D. Baldus
|
| Street address |
Hindenburgdamm 30
|
| City |
Berlin |
| State/province |
Berlin |
| ZIP/Postal code |
12203 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA222990 |
Less...
More...