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Series GSE51258 Query DataSets for GSE51258
Status Public on Oct 19, 2013
Title ERG induced mesenchymal like gene signature
Organism Homo sapiens
Experiment type Expression profiling by array
Summary ERG overexpression was conducted in stably transfected K562 cell line with a tet-on inducible plasmid habouring ERG3. Prolonged induction of ERG (8 days) produced spindle cell shape changes whereas non-induced cells retained the round morphology. In oder to determine the genes responsible for inducing cell shape changes, a genome wide transcriptional screen was conducted.
Overall design Three clones that potently induced ERG overexpression (8 days) with the corresponding non-induced cells were hybridized.
Contributor(s) Mochmann LH, Neumann M, Nowak V, Hofmann WK, Baldus CD
Citation(s) 24504051
Submission date Sep 27, 2013
Last update date Mar 25, 2019
Contact name Claudia D Baldus
Organization name Charite
Department Hematology and Oncology
Lab Claudia D. Baldus
Street address Hindenburgdamm 30
City Berlin
State/province Berlin
ZIP/Postal code 12203
Country Germany
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (6)
GSM1241302 K562 pTRE ERG CL4 dox
GSM1241303 K562 pTRE ERG CL4 no dox
GSM1241304 K562 pTRE ERG CL9 dox
BioProject PRJNA222990

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Supplementary file Size Download File type/resource
GSE51258_RAW.tar 20.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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