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Series GSE50121 Query DataSets for GSE50121
Status Public on Nov 18, 2013
Title Runx3 function in IL-2-activated splenic CD8+ T cells.
Organism Mus musculus
Experiment type Expression profiling by array
Summary CD8+T cells are immune cells that recognize foreign antigens on infected and tumor cells, leading to cytokine-dependent expansion and activation of cytotoxicity towards the targets.
 
Overall design To identify Runx3 regulated genes, CD8+ T cells were isolated from spleen of WT and Runx3-/- mice . Six samples (3 WT and 3 Runx3-/-) of CD8+ T cells were separately obtained from individual mice, TCR activated and cultured for 4 days with IL-2.
 
Contributor(s) Lotem J, Leshkowitz D, Groner Y
Citation(s) 24236182
Submission date Aug 22, 2013
Last update date Mar 04, 2019
Contact name Joseph Lotem
E-mail(s) joseph.lotem@weizmann.ac.il
Phone 972-8-934-2342
Organization name Weizmann institute of science
Department Molecular genetics
Street address P.O.B 26
City Rehovot
ZIP/Postal code 76100
Country Israel
 
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (6)
GSM1214459 CD8_IL2_wt1
GSM1214460 CD8_IL2_wt2
GSM1214461 CD8_IL2_wt3
This SubSeries is part of SuperSeries:
GSE50131 The transcription program of Runx3 in natural killer cells and CD8+ T cells
Relations
BioProject PRJNA216117

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50121_RAW.tar 22.9 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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