|
| Status |
Public on Nov 18, 2013 |
| Title |
Runx3 function in IL-2-activated splenic CD8+ T cells. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
CD8+T cells are immune cells that recognize foreign antigens on infected and tumor cells, leading to cytokine-dependent expansion and activation of cytotoxicity towards the targets.
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| |
|
| Overall design |
To identify Runx3 regulated genes, CD8+ T cells were isolated from spleen of WT and Runx3-/- mice . Six samples (3 WT and 3 Runx3-/-) of CD8+ T cells were separately obtained from individual mice, TCR activated and cultured for 4 days with IL-2.
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| |
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| Contributor(s) |
Lotem J, Leshkowitz D, Groner Y |
| Citation(s) |
24236182 |
| |
| Submission date |
Aug 22, 2013 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Joseph Lotem |
| E-mail(s) |
joseph.lotem@weizmann.ac.il
|
| Phone |
972-8-934-2342
|
| Organization name |
Weizmann institute of science
|
| Department |
Molecular genetics
|
| Street address |
P.O.B 26
|
| City |
Rehovot |
| ZIP/Postal code |
76100 |
| Country |
Israel |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE50131 |
The transcription program of Runx3 in natural killer cells and CD8+ T cells |
|
| Relations |
| BioProject |
PRJNA216117 |
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