|
| Status |
Public on Apr 21, 2014 |
| Title |
Human BRAF-V600E melanoma cell lines drug sensitive vs drug resistant |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
aCGH of human melanoma cell lines comparing parental (drug sensitve) vs isogenic drug resistant-derived subline
|
| |
|
| Overall design |
Two condition experiment: two BRAF-V600E mutant cell lines (drug sensitive - parental baseline) vs two derived sublines after chronic exposure to the MEK inhibitor trametinib (drug resistant) are compared
|
| |
|
| Contributor(s) |
Nathanson KL, Villanueva J, Wubbenhorst B |
| Citation(s) |
24055054 |
| |
| Submission date |
Aug 01, 2013 |
| Last update date |
Mar 21, 2017 |
| Contact name |
Katherine Nathanson |
| E-mail(s) |
knathans@exchange.upenn.edu
|
| Organization name |
Perelman School of Medicine at the University of Pennsylvania
|
| Street address |
421 Curie Blvd
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19103 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9777 |
Agilent-021850 SurePrint G3 Human CGH Microarray (Feature Number version) |
|
| Samples (4)
|
| GSM1199178 |
BRAF-V600E melanoma_451Lu_parental_drug senstive |
| GSM1199179 |
BRAF-V600E melanoma_451Lu_subline_drug resistant |
| GSM1199180 |
BRAF-V600E melanoma_Mel1617_parental_drug senstive |
| GSM1199181 |
BRAF-V600E melanoma_Mel1617_subline_drug resistant |
|
| Relations |
| BioProject |
PRJNA213902 |
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