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| Status |
Public on Apr 20, 2013 |
| Title |
Gene Expression Analysis of Dermatomyositis Skin |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The purpose of this study was to use global gene expression analysis to determine major functional pathways and genes dysregulated in the skin of active rashes of dermatomyositis patients. These data will be used to help assign a diagnosis to skin biopsies from patients with rashes that are not clearly dermatomyositis. In addition, we will correlate gene expression changes with specific histopathologic changes in skin biopsies that are taken adjacent to those analyzed for gene expression analysis. Finally, these data will be used to search for genes and pathways that are associated with clinical outcomes and autoantibody status in this cohort of patients.
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| |
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| Overall design |
Gene expression profiling of healthy donor and dermatomyositis patient skin biopsy specimens.
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| |
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| Contributor(s) |
Morehouse CA |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 20, 2013 |
| Last update date |
Dec 09, 2020 |
| Contact name |
Christopher Allen Morehouse |
| Organization name |
Medimmune LLC
|
| Street address |
One Medimmune Way
|
| City |
Gaithersburg |
| State/province |
MD |
| ZIP/Postal code |
20878 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (52)
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| Relations |
| BioProject |
PRJNA198446 |
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