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Series GSE45551 Query DataSets for GSE45551
Status Public on Aug 17, 2014
Title Prevention of Mouse AA with IL-15 pathway inhibitors
Organism Mus musculus
Experiment type Expression profiling by array
Summary Our goal was to identify gene expression patterns that correlated with prevention of autoimmune alopecia in C3H/HeJ mice following alopecic graft transplantation
skin from 3-5 mice were taken at 5/6 weeks and 12/13 weeks of drug administration following grafting; mice were treated with ruxolitinib (jak12i) by oral gavage, tofacitinib (jak3i) by osmotic pump, antiIL15R-beta antibody by i.p. injection, or control pbs by either ip injection, oral gavage, or osmotic pump. sham indicates mice that received no graft.
 
Overall design 3-5 biological replicates were taken at each time point for each treatment modality
 
Contributor(s) Jabbari A, Cerise JE, Christiano AM
Citation(s) 25129481
Submission date Mar 27, 2013
Last update date Feb 11, 2019
Contact name Ali Jabbari
Organization name University of Iowa
Street address 200 Hawkins Dr, 40025 PFP
City Iowa City
State/province IA
ZIP/Postal code 52242
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (48)
GSM1109116 week5-il15rb-1
GSM1109117 week5-il15rb-2
GSM1109118 week5-il15rb-3
Relations
BioProject PRJNA194564

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45551_RAW.tar 177.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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