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Series GSE44821 Query DataSets for GSE44821
Status Public on Mar 05, 2013
Title Genome-wide occupancy profile of Tbx3 in adult mouse whole heart
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The contraction pattern of the heart relies on the activation and conduction of the electrical impulse. Perturbations of cardiac conduction have been associated with congenital and acquired arrhythmias as well as cardiac arrest. The pattern of conduction depends on the regulation of heterogeneous gene expression by key transcription factors and transcriptional enhancers. Here, we assessed the genome-wide occupation of conduction system–regulating transcription factors TBX3 in the mouse heart, uncovering cardiac enhancers throughout the genome. 
Overall design Examination of the cardiac transcription factor Tbx3 in adult mouse heart
Contributor(s) van den Boogaard M, Barnett P, Christoffels VM
Citation(s) 24936875
Submission date Mar 04, 2013
Last update date May 15, 2019
Contact name Vincent M. Christoffels
Phone 0205667821
Organization name Amsterdam UMC
Department Medical Biology
Lab Vincent Christoffels
Street address Meibergdreef 15 K2-159
City Amsterdam
State/province N/A (NA)
ZIP/Postal code 1105 AZ
Country Netherlands
Platforms (1)
GPL9318 AB SOLiD System 3.0 (Mus musculus)
Samples (1)
GSM1092105 Heart_Tbx3_ChIP-seq
BioProject PRJNA192178
SRA SRP019234

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE44821_RAW.tar 2.2 Gb (http)(custom) TAR (of BED, BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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