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Series GSE42958 Query DataSets for GSE42958
Status Public on Apr 03, 2013
Title Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Idax/Cxxc4 is the CXXC domain protein that preferentially binds unmethylated CpG sites in vitro. By performing genome-wide mapping of Idax/Cxxc4, we report here that Idax is preferentially enriched in CpG-rich regions in genome including the promoters containing CpG islands.
Overall design ChIP-seq binding site detection of Myc-Idax and Myc-IdaxDBM over cells expressing an empty vector in stable HEK293T cell lines; two replicates per condition (2x ChIP Myc-Idax, 2x ChIP Myc-IdaxDBM, 2xChIP empty vector)
Contributor(s) Chavez L, Aijo T, Ko M, Rao A
Citation(s) 23563267
Submission date Dec 17, 2012
Last update date May 15, 2019
Contact name Lukas Chavez
Organization name German Cancer Research Center (DKFZ)
Street address Im Neuenheimer Feld 280
City Heidelberg
ZIP/Postal code 69120
Country Germany
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (3)
GSM1054009 Myc_Idax_ChIP-seq
GSM1054010 Myc_IdaxDBM_ChIP-seq
GSM1054011 Empty_ChIP-seq
BioProject PRJNA183941
SRA SRP017579

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Supplementary file Size Download File type/resource
GSE42958_RAW.tar 260.0 Kb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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