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| Status |
Public on Aug 13, 2013 |
| Title |
Gene expression microarray analysis on the dentate gyrus of Schnurri-2 knockout and wild-type control mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice show behavioral abnormalities that strongly resemble those of schizophrenics. We performed gene expression microarray analysis of dentate gyri from Shn-2 knockout and wild-type control mice.
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| Overall design |
Dentate gyrus RNA isolated from six Shn-2 knockout and six control wild-type mice were compared.
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| Contributor(s) |
Takao K, Umemori J |
| Citation(s) |
23389689 |
| |
| Submission date |
Dec 06, 2012 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Juzoh Umemori |
| E-mail(s) |
jumemori@fujita-hu.ac.jp
|
| Organization name |
Fujita Health University
|
| Street address |
1-98 Kutsukakecho, Dengakugakubo
|
| City |
Toyoake |
| ZIP/Postal code |
470-1192 |
| Country |
Japan |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE42778 |
Gene expression microarray analysis on the medial prefrontal cortex and dentate gyrus of Schnurri-2 knockout and wild-type control mice |
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| Relations |
| BioProject |
PRJNA183119 |
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