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Series GSE41185 Query DataSets for GSE41185
Status Public on Sep 06, 2013
Title Potentiation of regulatory T cell stability and function via a neuropilin-1:semaphorin-4a axis
Organism Mus musculus
Experiment type Expression profiling by array
Summary Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a)
Overall design Sema treated and NRP1 knock outs were compared to untreated wild type T cell controls
Contributor(s) Delgoffe GM, Woo S, Tunis ME, Gravano DM, Guy C, Bettini ML, Vogel P, Finkelstein D, Bonnevier J, Workman CJ, Vignali DA
Citation(s) 23913274
Submission date Sep 27, 2012
Last update date Feb 11, 2019
Contact name David Finkelstein
Phone 9014953931
Organization name St Jude Children's Research Hospital
Department Computational Biology
Street address 332 N. Lauderdale St.
City Memphis
State/province TN
ZIP/Postal code 38105
Country USA
Platforms (2)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
GPL11180 [HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate
Samples (40)
GSM1010159 Treg activated cjw165
GSM1010160 Treg resting cjw173
GSM1010161 Treg activated cjw175
BioProject PRJNA176124

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41185_RAW.tar 93.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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