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Series GSE41021 Query DataSets for GSE41021
Status Public on Aug 16, 2013
Title Retinoic acid determines the in vivo fate-commitment of splenic pre-dendritic cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary Comparison of gene expression changes of FACS sorted splenic CD11b+CD8a- and CD11b-CD8a+ cDC subsets reconstituted in vivo following total body irradiation in combination with exogenous retinoic acid or vehicle control.
 
Overall design Mice maintained on a control diet were subjected to 6 Gy total body irradiation and then provided exogenous retinoic acid or vehicle control beginning on D(+)3 after irradiation. All treated mice also received adoptive T cell transfer of either Trp-1 CD4+ or Pmel-1 CD8+ T cells, rVV, and IL-2. Splenic cDCs were isolated on D(+)10 after total body irradiation by FACS sorting.
 
Contributor(s) Klebanoff CA, Ferreyra GA
Citation(s) 23999499
Submission date Sep 20, 2012
Last update date Dec 12, 2023
Contact name Gabriela A Ferreyra
E-mail(s) gferreyra@cc.nih.gov
Phone 301-435-2317
Organization name Clinical Center
Department CCMD
Street address 9000 Rockville Pike - Building 10 room 4D03
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (16)
GSM1006916 CD11b-CD8a+ with exogenous RA replicate 1
GSM1006917 CD11b-CD8a+ with exogenous RA replicate 2
GSM1006918 CD11b-CD8a+ with exogenous RA replicate 3
Relations
BioProject PRJNA175555

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41021_RAW.tar 68.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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