|
| Status |
Public on Dec 05, 2013 |
| Title |
Global mapping of estrogen receptor and histone modifications in breast tumor samples uncovers distinct patterns for aromatase inhibitor resistance |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
ChIP-seq on primary breast cancer tumor samples for Era, H3K4me3, H3K27me3. Patients had a poor or good outcome after aromatase inhibitor treatment. Differential binding patterns between good and poor outcome patients were identified for each marker, predicting response to treatment
|
| |
|
| Overall design |
comparing ER, H3K4me3 and H3K27me3 patterns between two breast cancer patient populations
|
| |
|
| Contributor(s) |
Zwart W, Velds A |
| Citation(s) |
24242068, 26484094 |
| |
| Submission date |
Sep 13, 2012 |
| Last update date |
Jul 31, 2019 |
| Contact name |
Wilbert Zwart |
| Organization name |
NKI
|
| Street address |
Plesmanlaan 121
|
| City |
Amsterdam |
| ZIP/Postal code |
1066CX |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (36)
|
|
| Relations |
| BioProject |
PRJNA175144 |
| SRA |
SRP015749 |
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