|
| Status |
Public on Dec 26, 2012 |
| Title |
Gene expression changes following knockdown of Kdm2b on mESCs |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In order to study the effects of Kdm2b binding at CpG islands, Kdm2b was knocked down in mouse embryonic stem cells using shRNA and gene expression profiled using Affymetrix arrays
Depletion of KDM2B affects the gene expression of a subset of polycomb targets
|
| |
|
| Overall design |
RNA from 4 samples stably expressing shKdm2b and 4 samples stably expressing a control shRNA was hybridized to Affymetrix Mouse Gene 1.0 ST Arrays
|
| |
|
| Contributor(s) |
Klose RJ, Sudbery I, Farcas AM, Lee S |
| Citation(s) |
23256043 |
| Submission date |
Sep 07, 2012 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Ian Sudbery |
| E-mail(s) |
i.sudbery@sheffield.ac.uk
|
| Organization name |
University of Sheffield
|
| Department |
Molecular Biology and Biotechnology
|
| Lab |
Sudbery Lab for Computational Genomics
|
| Street address |
Firth Court, Western Bank
|
| City |
Sheffield |
| ZIP/Postal code |
S11 8HG |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (8)
|
|
| This SubSeries is part of SuperSeries: |
| GSE41267 |
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands |
|
| Relations |
| BioProject |
PRJNA174681 |
Less...
More...