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Series GSE40632 Query DataSets for GSE40632
Status Public on Sep 09, 2014
Title Genome-wide analysis of the Integrator complex (HTS)
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary We investigated the genomic occupancy of INTS11, in normal condition and after stimulation of EGF. Total RNAPII was profiled in the presence or absence of INTS11, along with the Super Elongation Complex proteins AFF4 and ELL2. Additionally, we extensively examined the transcriptional response to EGF, before and after depletion of INTS11, using RNA-seq on ribosome-depleted total RNA and Global Run-on sequencing (GRO-seq).
Overall design Comparison of the genome-wide profiles of INTS11 and RNAPII in HeLa cells.
Contributor(s) Gardini A, Baillat D, Cesaroni M, Hu D, Shiekhattar R
Citation(s) 25201415
Submission date Sep 05, 2012
Last update date May 15, 2019
Contact name Alessandro Gardini
Phone 305-243-7394
Organization name University of Miami
Department Sylvester Comprehensive Cancer Center
Lab Ramin Shiekhattar
Street address 1501 NW 10 Avenue
City Miami
State/province FL
ZIP/Postal code 33136
Country USA
Platforms (2)
GPL10999 Illumina Genome Analyzer IIx (Homo sapiens)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (46)
GSM1405078 AFF4_CTRL_rep1
GSM1405079 AFF4_CTRL_EGF_rep1
GSM1405080 AFF4_DOX_rep1
This SubSeries is part of SuperSeries:
GSE58255 Genome-wide analysis of the Integrator complex
BioProject PRJNA174441
SRA SRP015419

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40632_RAW.tar 45.1 Gb (http)(custom) TAR (of BEDGRAPH, BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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