|
| Status |
Public on Mar 07, 2013 |
| Title |
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression signatures were measured in logarithmic growing cultures
Affymetrix HG-U133AV2 expression arrays were performed according to the manufacturer's directions using RNA extracted by Qiagen RNeasy from engineered human melanoma cells
|
| |
|
| Overall design |
Resulting expression signatures where derived based on phenotypic properties: tumor-like endpoints driven by MITF overexpression
|
| |
|
| Contributor(s) |
Widlund HR, Fisher DE |
| Citation(s) |
23477830 |
| |
| Submission date |
May 16, 2012 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Hans R WIDLUND |
| E-mail(s) |
hwidlund@bics.bwh.harvard.edu
|
| Phone |
6175255777
|
| Organization name |
Brigham and Women's Hospital
|
| Department |
Dermatology
|
| Lab |
Widlund lab
|
| Street address |
77 Avenue Louis Pasteur
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02445 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
|
| Samples (6)
|
| GSM931776 |
BRAF(V600E) engineered melanomas replicate 1 |
| GSM931777 |
BRAF(V600E) engineered melanomas replicate 2 |
| GSM931778 |
BRAF(V600E) engineered melanomas replicate 3 |
| GSM931779 |
BRAF(V600E)+MITF engineered melanomas replicate 1 |
| GSM931780 |
BRAF(V600E)+MITF engineered melanomas replicate 2 |
| GSM931781 |
BRAF(V600E)+MITF engineered melanomas replicate 3 |
|
| Relations |
| BioProject |
PRJNA167038 |
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