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| Status |
Public on Aug 25, 2016 |
| Title |
Expression data in lung tissue from moderate COPD patients, healthy smokers and nonsmokers |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Chronic obstructive pulmonary disease (COPD) is a progressive and irreversible chronic inflammatory lung disease. The abnormal inflammatory response of the lung, mainly to cigarette smoke, causes multiple cellular and structural changes affecting all of its compartments, which leads to disease progression. The molecular mechanisms underlying these pathological changes are still not fully understood
The aim of this study was to identify genes and molecular pathways potentially involved in the pathogenesis of COPD
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| Overall design |
Peripheral lung tissue samples from moderate COPD patients, smokers and nonsmokers were obtained. All patients were undergoing lung resection for localized carcinomas. RNA was extracted and processed for further hybridization on Affymetrix microarrays
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| Contributor(s) |
Bastos R, Kalko SG |
| Citation missing |
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| |
| Submission date |
May 04, 2012 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Ricardo Bastos |
| E-mail(s) |
rbastos@clinic.ub.es
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| Organization name |
IDIBAPS/University of Barcelona
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| Department |
Cell Biology, Neurosciences and Immunology
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| Street address |
Rosellón 149-153
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| City |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (38)
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| Relations |
| BioProject |
PRJNA163249 |
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