|
| Status |
Public on May 08, 2012 |
| Title |
A novel miRNA produced during lytic HSV-1 infection is important for efficient replication in tissue culture. |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
We report a HSV-1 encoded miRNA present during lytic infection that influences replication efficiency in a tissue culture model. miRNAs were identified using high-throughput sequencing of HSV-1 infected epithelial cells. Functional assays were performed by mutating the miRNA coding region and testing grow of the mutant in vitro.
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| |
|
| Overall design |
Construction of a miRNA library and sequencing to reveal novel viral miRNAs from lytically infected cells
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| |
|
| Contributor(s) |
Munson DJ, Burch AD |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 02, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
April D Burch |
| E-mail(s) |
aprilburch1203@yahoo.com
|
| Organization name |
Wadsworth Center/ SUNY Albany/ Berkshire School
|
| Department |
Infectious Diseases
|
| Lab |
Burch Lab
|
| Street address |
120 New Scotlant Ave
|
| City |
Albany |
| State/province |
NY |
| ZIP/Postal code |
12208 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10999 |
Illumina Genome Analyzer IIx (Homo sapiens) |
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| Samples (1) |
|
| Relations |
| BioProject |
PRJNA162879 |
| SRA |
SRP012612 |
