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Series GSE37616 Query DataSets for GSE37616
Status Public on Jun 21, 2012
Title Genome-wide microRNA expression analysis of clear cell Renal Cell Carcinoma by next generation deep sequencing
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary MicroRNAs (miRNAs), non-coding RNAs regulating gene expression, are frequently aberrantly expressed in human cancers. Next-generation deep sequencing technology enables genome-wide expression profiling of known miRNAs and discovery of novel miRNAs at unprecedented quantitative and qualitative accuracy. Deep sequencing was performed on 22 fresh frozen clear cell renal cell carcinoma (ccRCC), 11 non-tumoral renal cortex (NRC) samples and 2 ccRCC cell lines (n=35). The 22 ccRCCs patients belonged to 3 prognostic sub-groups, i.e. Those without disease recurrence, with recurrence and with metastatic disease at diagnosis
 
Overall design Deep sequencing was performed on 22 fresh frozen clear cell renal cell carcinoma (ccRCC), 11 non-tumoral renal cortex (NRC) samples and 2 ccRCC cell lines (n=35). The 22 ccRCCs patients belonged to 3 prognostic sub-groups, i.e. Those without disease recurrence, with recurrence and with metastatic disease at diagnosis.
 
Contributor(s) Osanto S, Qin Y, Buermans HP, Berkers J, Lerut E, Goeman J, van Poppel H
Citation(s) 22745662
Submission date Apr 26, 2012
Last update date Feb 21, 2019
Contact name Henk Buermans
E-mail h.buermans@lumc.nl
Phone +31715268558
Organization name Leiden University Medical Center
Department Human Genetics
Lab Leiden Genome Technology Center
Street address Albinusdreef 2
City Leiden
State/province ZH
ZIP/Postal code 2300 RC
Country Netherlands
 
Platforms (1)
GPL10999 Illumina Genome Analyzer IIx (Homo sapiens)
Samples (35)
GSM923251 NRC 30K1R_s5_AAGCCC
GSM923252 NRC 30K1R_s5_CCCCTT
GSM923253 NRC 42T2V_s1_AAGCCC
Relations
BioProject PRJNA162397
SRA SRP012546

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37616_RAW.tar 31.3 Mb (http)(custom) TAR (of TXT)
Raw data are available in SRA
Processed data provided as supplementary file

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