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| Status |
Public on May 01, 2012 |
| Title |
Identification of intermediate-sized non-coding RNAs involved in the UV-induced DNA damage response in C. elegans |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
We utilized high-throughput RNA-seq to uncover the intermediate-sized noncoding RNAs invovled in UV-DNA Damage Responses in C. elegans. 450 novel transfrags were discovered, some of which show dramatic expression change between the UV irradiation and control. This study should lead to a better understanding of the role of is-ncRNAs invovled in UV-DDR.
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| Overall design |
Examination of intermediate-sized transcripts (70-500nt) in L4 larvae of C. elegans strains, including wild-type (N2), UV-irradiated (N2-UV100J/m2) and NER-deficient mutant (xpa-1) strains.
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| Contributor(s) |
Li A, Wei G, Wang Y |
| Citation(s) |
23144846 |
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| Submission date |
Apr 05, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Guifeng Wei |
| E-mail(s) |
guifengwei@gmail.com
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| Organization name |
Institute of Biophysics, Chinese Academy of Sciences
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| Street address |
15 Datun Road
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| City |
Beijing |
| State/province |
Beijing |
| ZIP/Postal code |
100101 |
| Country |
China |
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| Platforms (1) |
| GPL9309 |
Illumina Genome Analyzer (Caenorhabditis elegans) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA157963 |
| SRA |
SRP012065 |
