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Series GSE36476 Query DataSets for GSE36476
Status Public on Mar 14, 2012
Title Gene expression in CD4 memory T cell responses with age
Organism Homo sapiens
Experiment type Expression profiling by array
Summary With increasing age, the ability of the immune system to protect against recurring infections or to control chronic infections erodes. The objective of the current study was to identify gene expression signatures in elderly CD4 T cell responses
 
Overall design Vβ2+ CD4 memory T cells from four 20-35 and four 70-75 year-old individuals were stimulated with toxic shock syndrome toxin (TSST) presented by myeloid dendritic cells (mDC) derived from young adults. Gene expression was examined at 16, 40 and 72 h after stimulation using Affymetrix arrays.
 
Contributor(s) Yu M, Goronzy JJ
Citation(s) 22434910
Submission date Mar 13, 2012
Last update date Aug 10, 2018
Contact name Mingcan Yu
Phone (650)723-9027
Fax (650)721-1251
Organization name Stanford University School of Medicine
Department Medicine: Immunology and Rheumatology
Lab Dr. Goronzy lab
Street address CCSR Bldg. Rm. 2215, 269 Campus Drive West
City Stanford
State/province CA
ZIP/Postal code 94305-5166
Country USA
 
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (32)
GSM894428 CD4 memory T cells_0_hour_Old-1
GSM894429 CD4 memory T cells_16_hour_Old-1
GSM894430 CD4 memory T cells_40_hour_Old-1
Relations
BioProject PRJNA153507

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36476_RAW.tar 81.6 Mb (http)(custom) TAR (of CEL, CHP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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