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| Status |
Public on Oct 01, 2012 |
| Title |
Modulation of activation-associated host cell gene expression by the apicomplexan parasite Theileria annulata |
| Organisms |
Theileria annulata; Bos taurus |
| Experiment type |
Expression profiling by array
|
| Summary |
The experiment investigates bovine gene expression in response to LPS in uninfected and Theileria annulata-infected cell cultures
A subset of genes are identified which are activated in response to LPS stimulation with further modulation due to parasite infection.
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| Overall design |
Six experimental conditions with three replicates per condition. Total RNA prepared from cell cultures. BL20 (uninfected bovine lymphosarcoma cell line), BL20 4 hours post-LPS stimulation, BL20 18 hours post-LPS, TBL (T. annulata infected bovine cell line), TBL 4 hours post-LPS, TBL 18 hours post-LPS. Each hydridisation represents bovine and parasite gene expression on a single channel and 2 technical replicates of each probeset are represented on the chip.
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| Contributor(s) |
Durrani Z, Weir W, Pillai S, Kinnaird J, Shiels B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Mar 12, 2012 |
| Last update date |
Oct 02, 2012 |
| Contact name |
William Weir |
| Organization name |
University of Glasgow
|
| Department |
Institute of Infection, Immunity and Inflammation
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| Lab |
Theileria lab
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| Street address |
Room 220, Henry Wellcome Building, Garscube Campus, Bearsden Road
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| City |
Glasgow |
| ZIP/Postal code |
G61 1QH |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL15339 |
NimbleGen B. Taurus and T. annulata 385K 080829_B_taurus_JK_EXP |
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| Samples (18)
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| GSM893185 |
Theileria annulata infected Bos taurus TBL20 control rep1 |
| GSM893186 |
Theileria annulata infected Bos taurus TBL20 control rep2 |
| GSM893187 |
Theileria annulata infected Bos taurus TBL20 control rep3 |
| GSM893188 |
Bos taurus BL20 LPS 4h rep1 |
| GSM893189 |
Bos taurus BL20 LPS 4h rep2 |
| GSM893190 |
Bos taurus BL20 LPS 4h rep3 |
| GSM893191 |
Theileria annulata infected Bos taurus TBL20 LPS 4h rep1 |
| GSM893192 |
Theileria annulata infected Bos taurus TBL20 LPS 4h rep2 |
| GSM893193 |
Theileria annulata infected Bos taurus TBL20 LPS 4h rep3 |
| GSM893194 |
Bos taurus BL20 LPS 18h rep1 |
| GSM893195 |
Bos taurus BL20 LPS 18h rep2 |
| GSM893196 |
Bos taurus BL20 LPS 18h rep3 |
| GSM893197 |
Theileria annulata infected Bos taurus TBL20 LPS 18h rep1 |
| GSM893198 |
Theileria annulata infected Bos taurus TBL20 LPS 18h rep2 |
| GSM893199 |
Theileria annulata infected Bos taurus TBL20 LPS 18h rep3 |
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| Relations |
| BioProject |
PRJNA153233 |
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