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Series GSE34961 Query DataSets for GSE34961
Status Public on Feb 22, 2012
Title Expression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML
Organism Mus musculus
Experiment type Expression profiling by array
Summary We evaluated gene expression changes in secondary recipient murine leukemia caused by retroviral overexpression of MLL-AF9. We compared wild-type (WT) leukemia cells with mutant leukemia cells after cre-mediated inactivation of a homozygous conditional allele for Ezh2, a component of the Polycomb Repressive Complex2.
 
Overall design For WT cells, 4 biological replicates were hybridized. For Ezh2-null cells, 5 biological replicates were hybridized.
 
Contributor(s) Neff T, Sinha AU, Armstrong SA
Citation(s) 22396593
Submission date Jan 09, 2012
Last update date Feb 11, 2019
Contact name Amit Sinha
E-mail(s) amit.sinha@childrens.harvard.edu
Phone 617-582-7579
Organization name Dana-Farber Cancer Institute
Department Pediatric Oncology
Lab Armstrong Lab
Street address 44 Binney St
City Boston
State/province MA
ZIP/Postal code 02135
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (9)
GSM859583 WT 2'MLL-AF9 BM-Cells, biological rep1
GSM859584 WT 2'MLL-AF9 BM-Cells, biological rep2
GSM859585 WT 2'MLL-AF9 BM-Cells, biological rep3
This SubSeries is part of SuperSeries:
GSE34963 The Polycomb Repressive Complex 2 Is Required For MLL-AF9 Leukemia
Relations
BioProject PRJNA156137

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE34961_RAW.tar 36.3 Mb (http)(custom) TAR (of CEL)
GSE34961_combined.CTL_EZH2.combat.gct.txt.gz 4.4 Mb (ftp)(http) TXT
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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