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Series GSE34650 Query DataSets for GSE34650
Status Public on Jun 30, 2012
Title A genomic signature of gene-environment interactions in C. elegans
Organism Caenorhabditis elegans
Experiment type Expression profiling by array
Summary The phenotype is an interplay between genetic and environmental components, however the relationship between these two is difficult to predict. For any particular environment only a handful of genes show gene environment interaction [refs]. This may imply that certain constrains prevent genes to participate in gene environment interaction that possibly could be used to predict potential targets for such interaction under different sets of environmental conditions.
Our approach was to culture 6 C. elegans strains (5 geographical isolates + 1 mutant straint) at 20°C, then split the culture into 5 conditions. We measured mRNA abundances in 4-cell stage embryos using microarray with three separately collected 50-embryo replicates collected for each combination of strain and environment.
 
Overall design 90 microarrays of C. elegans for 6 strains * 5 conditions in triplicates.
 
Contributor(s) Grishkevich V, Hashimshony T, Ben-Elazar S, Schott DS, Hunter C, Yanai I
Citation(s) 22669615
Submission date Dec 22, 2011
Last update date Feb 05, 2014
Contact name Itai Yanai
E-mail(s) yanai@technion.ac.il
Organization name Technion - Israel Institute of Technology
Department Biology
Lab Yanai
Street address Technion City
City Haifa
ZIP/Postal code 30200
Country Israel
 
Platforms (1)
GPL13394 Agilent-018561 C. elegans 15k gene expression microarray
Samples (90)
GSM852579 AB2_Control_1
GSM852580 CB4856_Control_1
GSM852581 RC301_Control_1
Relations
BioProject PRJNA151249

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE34650_RAW.tar 60.3 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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