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Series GSE33931 Query DataSets for GSE33931
Status Public on Jul 05, 2012
Title Expression data from mouse muscle
Organism Mus musculus
Experiment type Expression profiling by array
Summary The knock-out of calpain 3 (C3KO) is a murine model for calpainopathies wich shows a mild dystrophic phenotype with signs of muscle degeneration. Adult (A) mice show a more severe phenotype than young (Y) mice which only present inflammatory infiltrates in most severely affected muscles, such as the soleus. Other muscles (e.g. quadriceps) are much less affected.
We used microarray technology to compare gene expression profiles of young and adult muscles in wild-type (wt) and C3KO mice, in two types of muscle: soleus (affected) and quadriceps (much less affected).
 
Overall design 11 wt (7 adult and 4 young) and 11 C3KO (7 adult and 4 young) mice were used in this study for RNA extraction and hybridization on Affymetrix microarrays. The soleus and the quadriceps muscles were obtained from each mouse. All mice were males.
 
Contributor(s) Saenz A, Jaka O
Citation(s) 22820870
Submission date Nov 23, 2011
Last update date Feb 11, 2019
Contact name Amets Saenz
E-mail amets.saenzpena@osakidetza.net
Phone +34 943 00 70 61
Fax +34 943 00 70 61
Organization name Donostia Hospital
Lab Unidad Experimental
Street address PÂș dr Begiristain s/n
City San Sebastian
State/province Gipuzkoa
ZIP/Postal code 20.014
Country Spain
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (42)
GSM838939 S of wt A mouse M2-1
GSM838940 Q of wt A mouse M2-1
GSM838941 Q of wt A mouse M2-2
Relations
BioProject PRJNA148217

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE33931_RAW.tar 137.1 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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