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Series GSE32681 Query DataSets for GSE32681
Status Public on Oct 07, 2011
Title Alterations in gene expression in lacrimal and salivary glands of male NOD mice due to LTBR-Ig treatment relative to control antibody
Organism Mus musculus
Experiment type Expression profiling by array
Summary NOD mice were injected once a week with LTBR-Ig to block the LTBR-pathway, or with control monoclonal antibody MOPC from age 8 to 16 weeks old. Extraorbital lacrimal glands or submaxillary glands were dissected and total mRNA prepared. Each sample was either the combined lacrimals (2) from each mouse or individual salivary glands. There were 4 mice in each treatment group. Total mRNA was isolated and the quality was assessed using the Agilent 2100 Bioanalyzer (Agilent Technologies, Palo Alto, CA). Reverse transcription to prepare cDNA was performed using Invitrogen M-MLV system. The purpose was to determine changes in gene expression in glands due to blockade of the LTBR-pathway.
Overall design Differential Gene Expression in NOD mouse lacrimal and salivary glands after LTBR-Ig treatment
Contributor(s) Bienkowska J, Fava R, Browning J
Citation(s) 22044682
Submission date Oct 06, 2011
Last update date Feb 11, 2019
Contact name Jadwiga Bienkowska
Phone 6174602469
Organization name BiogenIdec
Street address 45 Fayette Str Apt 3
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (61)
GSM811082 ControlLacW12 LAC2
GSM811083 ControlLacW12 LAC3
GSM811084 ControlLacW12 LAC4
BioProject PRJNA146907

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Supplementary file Size Download File type/resource
GSE32681_RAW.tar 191.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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