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Series GSE32321 Query DataSets for GSE32321
Status Public on Jan 13, 2012
Title A Wnt-Bmp feedback circuit controls inter-tissue signaling dynamics in tooth organogenesis
Organism Mus musculus
Experiment type Expression profiling by array
Summary Gene expression profiling of the epithelial and mesenchymal compartments of the developing mouse tooth using Laser Capture Microdissected (LCM) or enzymatic treatment with Dispase to isolate the dental epithelial and mesenchymal tissue, over a developmental period from E10.0-E14.5. The data is also accessible from http://compbio.med.harvard.edu/ToothCODE/
 
Overall design The aim of the study is to investigate the the mode of epithelial-mesenchymal (E-M) interaction through analyzing global gene expression patterns. We collected wildtype spatiotemporal gene expression data and perturbation data from transcription factor knockouts and signaling molecule treatments to identify differentially regulated genes and reconstruct a gene regulatory network controlling E-M interaction in early tooth development.
Web link http://compbio.med.harvard.edu/ToothCODE/
 
Contributor(s) O'Connell DJ, Ho JW, Mammoto T, Ingber DE, Park PJ, Maas RL
Citation(s) 22234613
Submission date Sep 22, 2011
Last update date Jan 16, 2019
Contact name Joshua WK Ho
E-mail jwho@rics.bwh.harvard.edu
Organization name Brigham and Women's Hospital
Department Department of Medicine
Lab Division of Genetics
Street address 41 Avenue Louis Pasteur
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
 
Platforms (1)
GPL6887 Illumina MouseWG-6 v2.0 expression beadchip
Samples (105)
GSM800628 E11.5_Epi_1
GSM800629 E11.5_Epi_2
GSM800630 E11.5_Epi_3
Relations
BioProject PRJNA147281

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE32321_GSM800628_to_GSM800639_non-normalized.txt.gz 5.7 Mb (ftp)(http) TXT
GSE32321_GSM800640_to_GSE800657_non-normalized.txt.gz 7.8 Mb (ftp)(http) TXT
GSE32321_GSM800658_to_GSM800660_non-normalized.txt.gz 2.4 Mb (ftp)(http) TXT
GSE32321_GSM800661_to_GSM800672_non-normalized.txt.gz 4.6 Mb (ftp)(http) TXT
GSE32321_GSM800673_to_GSM800708_non-normalized.txt.gz 22.1 Mb (ftp)(http) TXT
GSE32321_GSM800709_to_GSM800732_non-normalized.txt.gz 15.0 Mb (ftp)(http) TXT
GSE32321_RAW.tar 15.8 Mb (http)(custom) TAR
Raw data is available on Series record
Processed data included within Sample table

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