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| Status |
Public on Aug 14, 2015 |
| Title |
Transcriptome profile on epileptogenic zones of patients with neocortical epilepsy |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
In the present study, we used expression microarray to establish a transcriptome on epileptogenic zone versus irritative zone from removed brain tissues of patients affected with intractable neocortical epilepsies.
Our results showed that expression profiling of a total of 30,968 human genes in 10 patients brain samples.
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| Overall design |
A total of 10 patients were recruited in this study. Mean age and period of intractable neocortical epilepsy were 19.8±2.5 and 13.7±2.3 years, respectively. After clinical evaluatng by EEG, SPEC, MRI, and v-EEG, patients were performed with surgical removal of epileptogenic zone and irritative zone. Removed surgical samples were obtained snap-frozen on dry ice for total RNA extraction commissined to Phalanx Biotech Group, Taiwan. RNA samples were evaluated using Human OneArray TM with 30,968 human genome probes.
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| Contributor(s) |
Hsin Y, Tsen H, Harnod T, Liu IY |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 29, 2011 |
| Last update date |
Aug 14, 2015 |
| Contact name |
Ingrid Liu |
| E-mail(s) |
ycliu@mail.tcu.edu.tw
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| Organization name |
Tzu Chi University
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| Department |
Molecular Biology and Human Genetics
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| Street address |
E411, 701, Section 3 Chung Yang Road
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| City |
Hualien |
| ZIP/Postal code |
970 |
| Country |
Taiwan |
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| Platforms (1) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA145345 |
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