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| Status |
Public on Jul 23, 2011 |
| Title |
CGH analysis of haploid ES cells |
| Organism |
Mus musculus |
| Experiment type |
Genome variation profiling by genome tiling array
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| Summary |
DNA samples of haploid ES cells and control DNA were compared to genomic DNA of the C57B/6 inbred mouse strain on a NimbleGen Mouse CGH 3x720K Whole-Genome Tiling Array (Build MM9), (GPL10989)
DNA samples of haploid ES cells and control DNA were compared to genomic DNA of the 129/Sv inbred mouse strain on a NimbleGen Mouse CGH 3x720K Whole-Genome Tiling Array (Build MM9), (GPL10989)
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| Overall design |
this analysis was performed to analyse copy number variations in haploid mouse ES cells from different genetic backgrounds. Male C57/B6 DNA was used as control. To identify CNVs based on the different genetic background control experiments comparing DNA from the inbred CBA and a mixed transgeneic mouse strain were performed.
this analysis was performed to analyse copy number variations in haploid mouse ES cells from different genetic backgrounds. Male 129/Sv kidney DNA was used as reference.
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| Contributor(s) |
Leeb M, Wutz A, Smith A |
| Citation(s) |
21900896, 22912412 |
| |
| Submission date |
Jul 18, 2011 |
| Last update date |
Oct 05, 2012 |
| Contact name |
Martin Leeb |
| E-mail(s) |
martin.leeb@univie.ac.at
|
| Organization name |
University of Vienna
|
| Department |
Max Perutz Labs
|
| Street address |
Dr.-Bohr-Gasse 9/3
|
| City |
Vienna |
| ZIP/Postal code |
1030 |
| Country |
Austria |
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| Platforms (1) |
| GPL10989 |
NimbleGen Mouse CGH 3x720K Whole-Genome Tiling Array (Build MM9) [080603_MM9_WG_CGH_HX3] |
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| Samples (8)
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| GSM762948 |
haploid ES cell line HAP1 p25 vs male somatic C57B/6 gDNA |
| GSM762949 |
haploid ES cell line HAP2 p18 vs male somatic C57B/6 gDNA |
| GSM762950 |
haploid ES cell line HTG1 p11 vs male somatic C57B/6 gDNA |
| GSM762951 |
haploid ES cell line HTG2 p11 vs male somatic C57B/6 gDNA |
| GSM762952 |
CBA male somatic vs male somatic C57B/6 gDNA |
| GSM762953 |
mixed transgenic HTG male somatic vs male somatic C57B/6 gDNA |
| GSM922002 |
haploid ES cell line H129-1 p17 1 sort vs male somatic 129/Sv gDNA |
| GSM922003 |
haploid ES cell line H129-1 p12 1 sort vs male somatic 129/Sv gDNA |
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| This SubSeries is part of SuperSeries: |
| GSE30879 |
Expression and CGH analysis of haploid ES cells |
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| Relations |
| BioProject |
PRJNA154725 |
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