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Status |
Public on Dec 31, 2011 |
Title |
Metabolic switching in Streptomyces coelicolor wild type, time series under glutamate depletion condition |
Platform organism |
Streptomyces coelicolor A3(2) |
Sample organism |
Streptomyces coelicolor |
Experiment type |
Expression profiling by array
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Summary |
During the lifetime of a fermenter culture, the soil bacterium S. coelicolor undergoes a major metabolic switch from exponential growth to antibiotic production. We have studied gene expression patterns during this switch, using a specifically designed Affymetrix GeneChip and a high-resolution time-series of fermenter-grown samples. This time series was conducted using medium leading to glutamate depletion and the cultivation conditions as published in Nieselt et al. BMC Genomics 2010, performed with the Streptomyces coelicolor wild type strain M145E.
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Overall design |
30 samples, no replicates; one hour resolution from 20-32h and 40-42h; half our resolution from 32-40 h; two hour resolution 44-58h; sample missing for 29 and 34 h
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Contributor(s) |
Waldvogel E, Herbig A, Battke F, Nentwich M, Nieselt K, Ellingsen TE, Wentzel A, Hodgson DA, Wohlleben W, Mast Y |
Citation(s) |
22033567 |
Submission date |
Jul 12, 2011 |
Last update date |
Sep 16, 2012 |
Contact name |
Kay Nieselt |
E-mail(s) |
kay.nieselt@uni-tuebingen.de
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Phone |
(+49) 70712978981
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Organization name |
Institute for Bioinformatics and Medical Informatics
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Department |
Department for Computer Science
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Lab |
Integrative Transcriptomics
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Street address |
Sand 14
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City |
Tübingen |
State/province |
DE |
ZIP/Postal code |
72076 |
Country |
Germany |
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Platforms (1) |
GPL9417 |
Streptomyces coelicolor Affymetrix array |
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Samples (30)
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This SubSeries is part of SuperSeries: |
GSE30571 |
The PII protein GlnK is a pleiotropic regulator for morphological differentiation and secondary metabolism in Streptomyces coelicolor |
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Relations |
BioProject |
PRJNA154767 |