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Series GSE29538 Query DataSets for GSE29538
Status Public on Jun 01, 2011
Title Expression data of small intestine crypts and villi from mice with nutritional and genetic risk factors for intestinal tumors
Organism Mus musculus
Experiment type Expression profiling by array
Summary Nutritional and genetic risk factors for intestinal tumors are additive on mouse tumor phenotypes, demonstrating that diet and genetic factors impact risk by distinct combinatorial mechanisms. We analyzed expression profiles of small intestine crypts and villi from mice with nutritional and genetic risk factors. The results advanced our understanding of the mechanistic roles played by major risk factors in the pathogenesis of intestinal tumors.
 
Overall design Small intestine crypts and villi from mice with nutritional (Ain76A, NWD1, and NWD2) and genetic risk factors (WT, Apc1638N/+ and p21-/-) were collected for RNA extraction and analysis using the Affymetrix 3' IVT expression microarray. Three or four replicates per tissue/risk factor.
 
Contributor(s) Wang D, Peregrina K, Dhima E, Lin EY, Mariadason JM, Augenlicht LH
Citation(s) 21652773
Submission date May 25, 2011
Last update date Feb 11, 2019
Contact name DONGHAI WANG
E-mail dhwang78@gmail.com, leonard.augenlicht@einstein.yu.edu
Organization name Montefiore Medical Center
Street address 111 E210 St
City Bronx
State/province NY
ZIP/Postal code 10467
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (47)
GSM731248 crypt_wild type_rep1
GSM731249 crypt_wild type_rep2
GSM731250 crypt_wild type_rep3
Relations
BioProject PRJNA141437

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE29538_RAW.tar 171.3 Mb (http)(custom) TAR (of CEL, CHP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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