|
| Status |
Public on Oct 17, 2013 |
| Title |
Conditional knockout of Sox2 in embryonic and trophoblast stem cells. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To compare the transcriptional networks governed by Sox2 in embryonic stem (ES) cells and trophoblast stem (TS) cells, we performed whole-genome expression analysis after tetracycline (Tet)-induced knockout of Sox2 in each cell type.
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| |
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| Overall design |
A Tet-inducible Sox2 knockout ES cell line 2TS22C or its derivative TSC line 22CEROH2-TSC1 were treated with Tet for 4 days. A total of 12 samples from ES or TS cells cultured with or without Tet were analyzed in three biological replicates.
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| |
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| Contributor(s) |
Adachi K, Nikaido I, Ueda HR, Niwa H |
| Citation(s) |
24120664 |
| |
| Submission date |
Apr 07, 2011 |
| Last update date |
Mar 06, 2018 |
| Contact name |
Itoshi NIKAIDO |
| E-mail(s) |
itoshi.nikaido@riken.jp
|
| Organization name |
RIKEN
|
| Department |
Center for Biosystems Dynamics Research
|
| Lab |
Laboratory for Bioinformatics Research
|
| Street address |
2-1 Hirosawa
|
| City |
Wako |
| State/province |
Saitama |
| ZIP/Postal code |
351-0198 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE28455 |
Sox2-regulatory networks in embryonic and trophoblast stem cells |
|
| Relations |
| BioProject |
PRJNA143237 |
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