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Series GSE28450 Query DataSets for GSE28450
Status Public on Sep 10, 2011
Title aCGH analysis of familial Alzheimer’s disease with presenilin 2 mutation patient-specific induced pluripotent stem cells
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary We established two clones of induced pluripotent stem cells (iPSC) with the presenilin 2 mutation, N141 (PS2-1 iPSC and PS2-2 iPSC) by retroviral transduction of primary human fibroblasts. To detect the copy number dependent gene expression profiles in primary fibroblast carrying the presenilin 2 mutation N141(before reprogramming) and PS2-1 iPSC and PS2-2 iPSC(after reprogramming), this experiment was designed.
Overall design Genomic DNA of primary fibroblasts carrying the presenilin 2 mutation N141 and undifferentiated PS2-1 iPSC and PS2-2 iPSC were collected. Then, they were applied in this experiment.
Contributor(s) Yagi T, Ito D
Citation(s) 21900357
Submission date Apr 07, 2011
Last update date Dec 06, 2012
Contact name Takuya Yagi
Organization name Keio University
Street address 35-Shinanomachi Shinjuku-ku
City Tokyo
ZIP/Postal code 160-8582
Country Japan
Platforms (1)
GPL10123 Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version)
Samples (3)
GSM703156 PS2-1 iPSC
GSM703157 PS2-2 iPSC
GSM703158 PS2 fibroblast
BioProject PRJNA139147

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28450_RAW.tar 56.1 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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