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| Status |
Public on Mar 06, 2012 |
| Title |
Transcriptomic analysis of human retinal detachment (RD) reveals both inflammation and photoreceptor death |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment.
Data analysis reveals major involvement of the immune response in the disease and interindividual variation was monitored to unravel a second crucial aspect of the pathological process, the death of photoreceptor cells.
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| Overall design |
In total 38 surgical specimens (samples) were analyzed, 19 represent biopsies from patients with retinal detachment (RD) and 19 represent contral samples without retinal detachment.
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| Contributor(s) |
Delyfer M, Raffelsberger W, Mercier D, Korobelnik J, Gaudric A, Charteris DG, Tadayoni R, Metge F, Caputo G, Barale P, Ripp R, Muller J, Poch O, Sahel J, Leveillard T |
| Citation(s) |
22174898 |
| Submission date |
Mar 23, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Wolfgang Raffelsberger |
| E-mail(s) |
w.raffelsberger@unistra.fr
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| Organization name |
IGBMC
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| Department |
DBGS
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| Lab |
LBGI
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| Street address |
1 rue Laurent Fries
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| City |
Illkirch/Strasbourg |
| ZIP/Postal code |
67404 |
| Country |
France |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (38)
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| Relations |
| BioProject |
PRJNA139819 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE28133_RAW.tar |
282.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Raw data provided as supplementary file |
| Processed data included within Sample table |
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