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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 31, 2024 |
| Title |
Single-cell transcriptomic atlas of enteroendocrine cells along the murine gastrointestinal tract. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Third-party reanalysis
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| Summary |
Enteroendocrine cells (EECs) produce over 20 gut hormones which contribute to intestinal physiology, nutrient metabolism and the regulation of food intake. The objective of this study was to generate a comprehensive transcriptomic map of mouse EECs from the stomach to the rectum.
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| Overall design |
EECs were purified by flow-cytometry from the stomach, upper small intestine, lower small intestine, caecum and large intestine of NeuroD1-Cre mice, and analysed by single cell RNA sequencing.
Neurod1-Cre, large intestine, scRNA-seq; re-analysis of GSE137572
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| Contributor(s) |
Smith CA, Gribble FM |
| Citation(s) |
39378212 |
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| Submission date |
Jun 13, 2024 |
| Last update date |
Nov 21, 2024 |
| Contact name |
Fiona Gribble |
| Organization name |
University of Cambridge
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| Department |
Medical Research Laboratories
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| Street address |
Box 289 Addenbrooke's Hospital, Hills Road
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| City |
Cambridge |
| State/province |
Cambridgeshire |
| ZIP/Postal code |
CB2 0QQ |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (4)
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| GSM8327069 |
Neurod1-Cre, stomach, scRNA-seq |
| GSM8327070 |
Neurod1-Cre, upper small intestine, scRNA-seq |
| GSM8327071 |
Neurod1-Cre, lower small intestine, scRNA-seq |
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| Relations |
| Reanalysis of |
GSM4081873 |
| Reanalysis of |
GSM4081874 |
| BioProject |
PRJNA1123675 |
| Data table header descriptions |
| GEO Sample |
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| GEO Series |
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| SRA Experiment |
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| BioSample |
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| BioProject |
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| Sample title |
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| Data table |
| GEO Sample |
GEO Series |
SRA Experiment |
BioSample |
BioProject |
Sample title |
| GSM4081873 |
GSE137572 |
SRX6859676 |
SAMN12773509 |
PRJNA565952 |
NeuroD Pos Enteroendocrine Cells from Large Intestine Replicate 1 |
| GSM4081874 |
GSE137572 |
SRX6859677 |
SAMN12773508 |
PRJNA565952 |
NeuroD Pos Enteroendocrine Cells from Large Intestine Replicate 2 |
Total number of rows: 2
| Supplementary file |
Size |
Download |
File type/resource |
| GSE269778_RAW.tar |
1.3 Gb |
(http)(custom) |
TAR (of H5, RDS) |
| GSE269778_clustermarkers.NeuroD1-EYFP.integrated.RDS.gz |
682.8 Kb |
(ftp)(http) |
RDS |
| GSE269778_countmatrix.NeuroD1-EYFP.LI-01.h5 |
6.7 Mb |
(ftp)(http) |
H5 |
| GSE269778_countmatrix.NeuroD1-EYFP.LI-02.h5 |
7.2 Mb |
(ftp)(http) |
H5 |
| GSE269778_seuratobject.NeuroD1-EYFP.LI.RDS.gz |
68.7 Mb |
(ftp)(http) |
RDS |
| GSE269778_seuratobject.NeuroD1-EYFP.integrated.RDS.gz |
1.4 Gb |
(ftp)(http) |
RDS |
SRA Run Selector |
| Raw data are available in SRA |
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