|
| Status |
Public on Jul 17, 2024 |
| Title |
Effect of chronic epinephrine exposure on gene expression in MIN6 cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Chronic exposure to epinephrine enhances the compensatory insulin secretion in MIN6 cells while persistently inhibiting cell proliferation. The molecular mechanisms underlying these phenomena were investigated through transcriptome sequencing, which identified differential mRNA transcriptional expression. This analysis has uncovered the pivotal signaling pathways that govern cellular function and destiny.
|
| |
|
| Overall design |
To explore the effects of chronic epinephrine on the functionality and fate of islet beta cells, we conducted an investigation using the MIN6 cell line. The cells were incubated with epinephrine, after which we performed an analysis of their gene expression profiles.
***************************************************************
Submitter states that missing raw files are due to file loss.
***************************************************************
|
| |
|
| Citation(s) |
39000139 |
| |
| Submission date |
Jun 12, 2024 |
| Last update date |
Jul 17, 2024 |
| Contact name |
Bingpeng Yao |
| E-mail(s) |
ybp962024847@email.swu.edu.cn
|
| Phone |
13368321844
|
| Organization name |
southwest university
|
| Street address |
Tiansheng Road 2
|
| City |
Chongqing |
| State/province |
-- Please Select -- |
| ZIP/Postal code |
400700 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA1123195 |
Less...
More...