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| Status |
Public on Apr 02, 2024 |
| Title |
Genome-wide CPD repair maps of Caenorhabditis elegans |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Other
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| Summary |
We have adapted the eXcision Repair-sequencing (XR-seq) method to generate single-nucleotide resolution dynamic repair maps of UV-induced cyclobutane pyrimidine dimers (CPD) photoproducts in the Caenorhabditis elegans (C. elegans) genome.
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| Overall design |
We employed XR-seq to evaluate genome-wide excision repair dynamics in WT, csb-1, and xpc-1 C. elegans following UV exposure.
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| Contributor(s) |
Kose C, Lindsey-Boltz L, Sancar A, Jiang Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 26, 2024 |
| Last update date |
Apr 03, 2024 |
| Contact name |
Yuchao Jiang |
| E-mail(s) |
yuchaojiang@tamu.edu
|
| Organization name |
Texas A&M University
|
| Street address |
3143 TAMU
|
| City |
College Station |
| State/province |
TX |
| ZIP/Postal code |
77843 |
| Country |
USA |
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| Platforms (1) |
| GPL32326 |
NextSeq 2000 (Caenorhabditis elegans) |
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| Samples (8)
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| GSM8170419 |
XR- seq csb-1 mutant C. elegans CPD 1h rep 1 |
| GSM8170420 |
XR- seq csb-1 mutant C. elegans CPD 1h rep 2 |
| GSM8170421 |
XR-seq WT C. elegans CPD 1h rep 1 |
| GSM8170422 |
XR-seq WT C. elegans CPD 1h rep 2 |
| GSM8170423 |
XR-seq WT no UV C. elegans CPD rep 1 |
| GSM8170424 |
XR-seq WT no UV C. elegans CPD rep 2 |
| GSM8170425 |
XR-seq xpc-1 mutant C. elegans mixed stages CPD 1h rep 1 |
| GSM8170426 |
XR-seq xpc-1 mutant C. elegans mixed stages CPD 1h rep 2 |
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| Relations |
| BioProject |
PRJNA1091964 |
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