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Status |
Public on Mar 09, 2024 |
Title |
Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
IFNγ-dependent remodelling of the myeloid immune landscape underlies control of IFNγ-insensitive tumors
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Overall design |
C57Bl6 WT mice were engrafted with the melanoma cell line B16 expressing OVA. CD45+ T cells were isolated by Fluorescence-activated cell sorting (FACS) from the tumor after 12 days and subjected to scRNA sequencing
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Contributor(s) |
Gérard A, Lau V |
Citation(s) |
39746898 |
|
Submission date |
Mar 06, 2024 |
Last update date |
Jan 03, 2025 |
Contact name |
Audrey Gerard |
E-mail(s) |
audrey.gerard@kennedy.ox.ac.uk
|
Phone |
01865612665
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Organization name |
The Kennedy Institute of Rheumatology
|
Street address |
Roosevelt Dr.
|
City |
Oxford |
ZIP/Postal code |
OX3 7FY |
Country |
United Kingdom |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (2) |
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Relations |
BioProject |
PRJNA1084756 |